Cargando…

Detecting intermediate protein conformations using algebraic topology

BACKGROUND: Understanding protein structure and dynamics is essential for understanding their function. This is a challenging task due to the high complexity of the conformational landscapes of proteins and their rugged energy levels. In particular, it is important to detect highly populated regions...

Descripción completa

Detalles Bibliográficos
Autores principales: Haspel, Nurit, Luo, Dong, González, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731496/
https://www.ncbi.nlm.nih.gov/pubmed/29244007
http://dx.doi.org/10.1186/s12859-017-1918-z