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Inhibition of lysosomal Ca(2+) signalling disrupts dendritic spine structure and impairs wound healing in neurons
A growing body of evidence suggests that lysosomes, which have traditionally been regarded as degradative organelles, can function as Ca(2+) stores, regulated by the second messenger nicotinic acid adenine dinucleotide phosphate (NAADP). We previously demonstrated that in hippocampal pyramidal neuro...
Autores principales: | Padamsey, Zahid, McGuinness, Lindsay, Emptage, Nigel J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731510/ https://www.ncbi.nlm.nih.gov/pubmed/29259727 http://dx.doi.org/10.1080/19420889.2017.1344802 |
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