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Role of sympathetic cotransmitter galanin on autonomic balance in heart failure: an active player or a bystander?

OBJECTIVE: Galanin, a cotransmitter similar to neuropeptide Y (NPY), aggravates autonomic imbalance in systolic heart failure (HF) by attenuating vagal tonus after burst sympathetic activity. In animal HF models, galanin antagonists have improved cardiac function. To determine whether galanin is a p...

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Detalles Bibliográficos
Autores principales: Gür, Demet Özkaramanlı, Sağbaş, Miray, Akyüz, Aydın, Güzel, Savaş, Alpsoy, Şeref, Güler, Niyazi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Kare Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731524/
https://www.ncbi.nlm.nih.gov/pubmed/28811392
http://dx.doi.org/10.14744/AnatolJCardiol.2017.7831