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Inference of genetic relatedness between viral quasispecies from sequencing data

BACKGROUND: RNA viruses such as HCV and HIV mutate at extremely high rates, and as a result, they exist in infected hosts as populations of genetically related variants. Recent advances in sequencing technologies make possible to identify such populations at great depth. In particular, these technol...

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Detalles Bibliográficos
Autores principales: Glebova, Olga, Knyazev, Sergey, Melnyk, Andrew, Artyomenko, Alexander, Khudyakov, Yury, Zelikovsky, Alex, Skums, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731608/
https://www.ncbi.nlm.nih.gov/pubmed/29244009
http://dx.doi.org/10.1186/s12864-017-4274-5