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Cisplatin alters the function and expression of N-type voltage-gated calcium channels in the absence of morphological damage of sensory neurons

Platinum-based chemotherapeutic agents, such as cisplatin, are still frequently used for treating various types of cancer. Besides its high effectiveness, cisplatin has several serious side effects. One of the most common side effects is dorsal root ganglion (DRG) neurotoxicity. However, the mechani...

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Detalles Bibliográficos
Autores principales: Leo, Markus, Schmitt, Linda-Isabell, Jastrow, Holger, Thomale, Jürgen, Kleinschnitz, Christoph, Hagenacker, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731623/
https://www.ncbi.nlm.nih.gov/pubmed/29166837
http://dx.doi.org/10.1177/1744806917746565