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Determination of complex subclonal structures of hematological malignancies by multiplexed genotyping of blood progenitor colonies

Current next-generation sequencing (NGS) technologies allow unprecedented insights into the mutational profiles of tumors. Recent studies in myeloproliferative neoplasms have further demonstrated that, not only the mutational profile, but also the order in which these mutations are acquired is relev...

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Detalles Bibliográficos
Autores principales: Nice, Francesca L., Massie, Charlie E., Klampfl, Thorsten, Green, Anthony R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Inc 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731633/
https://www.ncbi.nlm.nih.gov/pubmed/29024710
http://dx.doi.org/10.1016/j.exphem.2017.09.011