Enhancement of mouse hematopoietic stem/progenitor cell function via transient gene delivery using integration-deficient lentiviral vectors

Integration-deficient lentiviruses (IdLVs) deliver genes effectively to tissues but are lost rapidly from dividing cells. This property can be harnessed to express transgenes transiently to manipulate cell biology. Here, we demonstrate the utility of short-term gene expression to improve functional...

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Detalles Bibliográficos
Autores principales: Alonso-Ferrero, Maria E., van Til, Niek P., Bartolovic, Kerol, Mata, Márcia F., Wagemaker, Gerard, Moulding, Dale, Williams, David A., Kinnon, Christine, Waddington, Simon N., Milsom, Michael D., Howe, Steven J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Inc 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731634/
https://www.ncbi.nlm.nih.gov/pubmed/28911908
http://dx.doi.org/10.1016/j.exphem.2017.09.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731634/
https://www.ncbi.nlm.nih.gov/pubmed/28911908
http://dx.doi.org/10.1016/j.exphem.2017.09.003

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