Inhibition of merozoite invasion and transient de-sequestration by sevuparin in humans with Plasmodium falciparum malaria

SEVERE MALARIA: Even with the best available treatment, the mortality from severe Plasmodium falciparum malaria remains high. Typical features at death are high parasite loads and obstructed micro- vasculature. Infected erythrocytes (IE) containing mature parasites bind to the host receptor heparan...

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Detalles Bibliográficos
Autores principales: Leitgeb, Anna M., Charunwatthana, Prakaykaew, Rueangveerayut, Ronnatrai, Uthaisin, Chirapong, Silamut, Kamolrat, Chotivanich, Kesinee, Sila, Patima, Moll, Kirsten, Lee, Sue J., Lindgren, Maria, Holmer, Erik, Färnert, Anna, Kiwuwa, Mpungu S., Kristensen, Jens, Herder, Christina, Tarning, Joel, Wahlgren, Mats, Dondorp, Arjen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731734/
https://www.ncbi.nlm.nih.gov/pubmed/29244851
http://dx.doi.org/10.1371/journal.pone.0188754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731734/
https://www.ncbi.nlm.nih.gov/pubmed/29244851
http://dx.doi.org/10.1371/journal.pone.0188754

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