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Acid Sphingomyelinase Inhibition Prevents Hemolysis During Erythrocyte Storage

BACKGROUND/AIMS: During storage, units of human red blood cells (pRBCs) experience membrane destabilization and hemolysis which may cause harm to transfusion recipients. This study investigates whether inhibition of acid sphingomyelinase could stabilize erythrocyte membranes and prevent hemolysis du...

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Detalles Bibliográficos
Autores principales: Hoehn, Richard S., Jernigan, Peter L., Chang, Alex L., Edwards, Michael J., Caldwell, Charles C., Gulbins, Erich, Pritts, Timothy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731776/
https://www.ncbi.nlm.nih.gov/pubmed/27352097
http://dx.doi.org/10.1159/000445627