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The structural basis for dynamic DNA binding and bridging interactions which condense the bacterial centromere

The ParB protein forms DNA bridging interactions around parS to condense DNA and earmark the bacterial chromosome for segregation. The molecular mechanism underlying the formation of these ParB networks is unclear. We show here that while the central DNA binding domain is essential for anchoring at...

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Detalles Bibliográficos
Autores principales: Fisher, Gemma LM, Pastrana, César L, Higman, Victoria A, Koh, Alan, Taylor, James A, Butterer, Annika, Craggs, Timothy, Sobott, Frank, Murray, Heath, Crump, Matthew P, Moreno-Herrero, Fernando, Dillingham, Mark S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731820/
https://www.ncbi.nlm.nih.gov/pubmed/29244022
http://dx.doi.org/10.7554/eLife.28086