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Synthetic lethal genetic interactions between Rad54 and PARP-1 in mouse development and oncogenesis
Mutations in DNA repair pathways are frequent in human cancers. Hence, gaining insights into the interaction of DNA repair genes is key to development of novel tumor-specific treatment strategies. In this study, we tested the functional relationship in development and oncogenesis between the homolog...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731848/ https://www.ncbi.nlm.nih.gov/pubmed/29254138 http://dx.doi.org/10.18632/oncotarget.10479 |