Synthetic lethal genetic interactions between Rad54 and PARP-1 in mouse development and oncogenesis

Mutations in DNA repair pathways are frequent in human cancers. Hence, gaining insights into the interaction of DNA repair genes is key to development of novel tumor-specific treatment strategies. In this study, we tested the functional relationship in development and oncogenesis between the homolog...

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Detalles Bibliográficos
Autores principales: Tanori, Mirella, Casciati, Arianna, Berardinelli, Francesco, Leonardi, Simona, Pasquali, Emanuela, Antonelli, Francesca, Tanno, Barbara, Giardullo, Paola, Pannicelli, Alessandro, Babini, Gabriele, De Stefano, Ilaria, Sgura, Antonella, Mancuso, Mariateresa, Saran, Anna, Pazzaglia, Simonetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731848/
https://www.ncbi.nlm.nih.gov/pubmed/29254138
http://dx.doi.org/10.18632/oncotarget.10479

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