Cargando…

Novel allylated monocarbonyl analogs of curcumin induce mitotic arrest and apoptosis by reactive oxygen species-mediated endoplasmic reticulum stress and inhibition of STAT3

Curcumin is a promising active compound from a natural source and is extensively being tested in clinical trials because of its bio-functional properties. However, poor bioavailability has hampered its clinical application. Numerous attempts have been made in our laboratory to discover analogs of cu...

Descripción completa

Detalles Bibliográficos
Autores principales: Rajamanickam, Vinothkumar, Zhu, Heping, Feng, Chen, Chen, Xi, Zheng, Hailun, Xu, Xiaohong, Zhang, Qianqian, Zou, Peng, He, Guodong, Dai, Xuanxuan, Yang, Xi, Wang, Yi, Liu, Zhiguo, Liang, Guang, Guo, Guilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731860/
https://www.ncbi.nlm.nih.gov/pubmed/29254150
http://dx.doi.org/10.18632/oncotarget.20924