Casticin inhibits interleukin-1β–induced ICAM-1 and MUC5AC expression by blocking NF-κB, PI3K-Akt, and MAPK signaling in human lung epithelial cells

The compound casticin, isolated from Vitex rotundifolia, exerts anti-inflammatory effects and causes apoptosis of cancer cells. In this study, we explored the anti-inflammatory effects of casticin and modulation of cyclooxygenase (COX)-2, intercellular adhesion molecule 1 (ICAM-1), and mucin 5AC (MU...

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Detalles Bibliográficos
Autores principales: Liou, Chian-Jiun, Huang, Wen-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731865/
https://www.ncbi.nlm.nih.gov/pubmed/29254155
http://dx.doi.org/10.18632/oncotarget.20933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731865/
https://www.ncbi.nlm.nih.gov/pubmed/29254155
http://dx.doi.org/10.18632/oncotarget.20933

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