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Cerebrospinal fluid metabolomic profiles can discriminate patients with leptomeningeal carcinomatosis from patients at high risk for leptomeningeal metastasis

PURPOSE: Early diagnosis of leptomeningeal carcinomatosis (LMC) is necessary to improve outcomes of this formidable disease. However, cerebrospinal fluid (CSF) cytology is frequently false negative. We examined whether CSF metabolome profiles can be used to differentiate patients with LMC from patie...

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Detalles Bibliográficos
Autores principales: Yoo, Byong Chul, Lee, Jun Hwa, Kim, Kyung-Hee, Lin, Weiwei, Kim, Jong Heon, Park, Jong Bae, Park, Hyun Jin, Shin, Sang Hoon, Yoo, Heon, Kwon, Ji Woong, Gwak, Ho-Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731867/
https://www.ncbi.nlm.nih.gov/pubmed/29254157
http://dx.doi.org/10.18632/oncotarget.20983