Osteopontin production by TM4SF4 signaling drives a positive feedback autocrine loop with the STAT3 pathway to maintain cancer stem cell-like properties in lung cancer cells

Transmembrane 4 L6 family proteins have been known to promote cancer. In this study, we demonstrated that transmembrane 4 L6 family member 4 (TM4SF4), which is induced by γ-radiation in non-small cell lung cancer (NSCLC) cells, is involved in epithelial-to-mesenchymal transition (EMT) and cancer ste...

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Detalles Bibliográficos
Autores principales: Choi, Soo Im, Kim, Seo Yoen, Lee, Jei Ha, Kim, Jung Yul, Cho, Eun Wie, Kim, In-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731874/
https://www.ncbi.nlm.nih.gov/pubmed/29254164
http://dx.doi.org/10.18632/oncotarget.21021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731874/
https://www.ncbi.nlm.nih.gov/pubmed/29254164
http://dx.doi.org/10.18632/oncotarget.21021

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