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Targeting viperin improves diet-induced glucose intolerance but not adipose tissue inflammation

Viperin is an interferon-inducible antiviral protein, responsible for antiviral response to a variety of viral infections. Here, we show that silencing viperin by antisense oligonucleotides (ASO) protects against diet-induced glucose intolerance, and yet exacerbates adipose tissue inflammation. In h...

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Detalles Bibliográficos
Autores principales: Qi, Zhengtang, Xia, Jie, Xue, Xiangli, Liu, Jiatong, Liu, Weina, Ding, Shuzhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731885/
https://www.ncbi.nlm.nih.gov/pubmed/29254175
http://dx.doi.org/10.18632/oncotarget.20724