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Apelin13/APJ promotes proliferation of colon carcinoma by activating Notch3 signaling pathway

BACKGROUND: The link between Apelin (APL)/APL receptor (APJ) and Jagged (JAG)/Notch signaling pathways in colorectal cancer (CRC) has been poorly investigated. APL/APJ system, a potent angiogenic factor, is up-regulated in a variety of cancers. It contributes to tumor angiogenesis, and correlates wi...

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Detalles Bibliográficos
Autores principales: Chen, Tong, Liu, Ning, Xu, Guang-Meng, Liu, Tong-Jun, Liu, Ying, Zhou, Yan, Huo, Si-Bo, Zhang, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731907/
https://www.ncbi.nlm.nih.gov/pubmed/29254197
http://dx.doi.org/10.18632/oncotarget.21904