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High Tim-3 expression on AML blasts could enhance chemotherapy sensitivity

T-cell immunoglobulin and mucin domain-containing molecule3 (Tim-3) represents a novel mechanism of T-cell dysfunction and exhaustion. Tim-3 has also been identified in various solid tumors. However, the role of Tim-3 expression on blast cells in acute myeloid leukemia (AML) is not well understood....

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Detalles Bibliográficos
Autores principales: Xu, Liangjing, Xu, Jinge, Ma, Shoubao, Li, Xiaoli, Zhu, Mingqing, Chen, Suning, Han, Yue, Tang, Xiaowen, Fu, Zhengzheng, Qiu, Huiying, Yu, Jianhua, Wu, Depei, Wu, Xiaojin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5731937/
https://www.ncbi.nlm.nih.gov/pubmed/29254227
http://dx.doi.org/10.18632/oncotarget.22141