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High-Content Monitoring of Drug Effects in a 3D Spheroid Model

A recent decline in the discovery of novel medications challenges the widespread use of 2D monolayer cell assays in the drug discovery process. As a result, the need for more appropriate cellular models of human physiology and disease has renewed the interest in spheroid 3D culture as a pertinent mo...

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Detalles Bibliográficos
Autores principales: Mittler, Frédérique, Obeïd, Patricia, Rulina, Anastasia V., Haguet, Vincent, Gidrol, Xavier, Balakirev, Maxim Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732143/
https://www.ncbi.nlm.nih.gov/pubmed/29322028
http://dx.doi.org/10.3389/fonc.2017.00293