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High-Content Monitoring of Drug Effects in a 3D Spheroid Model
A recent decline in the discovery of novel medications challenges the widespread use of 2D monolayer cell assays in the drug discovery process. As a result, the need for more appropriate cellular models of human physiology and disease has renewed the interest in spheroid 3D culture as a pertinent mo...
Autores principales: | Mittler, Frédérique, Obeïd, Patricia, Rulina, Anastasia V., Haguet, Vincent, Gidrol, Xavier, Balakirev, Maxim Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732143/ https://www.ncbi.nlm.nih.gov/pubmed/29322028 http://dx.doi.org/10.3389/fonc.2017.00293 |
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