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Structure–Activity Relationship of Plesiomonas shigelloides Lipid A to the Production of TNF-α, IL-1β, and IL-6 by Human and Murine Macrophages

Plesiomonas shigelloides is a Gram-negative bacterium that is associated with diarrheal disease in humans. Lipopolysaccharide (LPS) is the main surface antigen and virulence factor of this bacterium. The lipid A (LA) moiety of LPS is the main region recognized by target cells of immune system. Here,...

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Detalles Bibliográficos
Autores principales: Kaszowska, Marta, Wojcik, Marta, Siednienko, Jakub, Lugowski, Czeslaw, Lukasiewicz, Jolanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732152/
https://www.ncbi.nlm.nih.gov/pubmed/29321776
http://dx.doi.org/10.3389/fimmu.2017.01741