Fibronectin is a stress responsive gene regulated by HSF1 in response to geldanamycin

Fibronectin is an extracellular matrix glycoprotein with key roles in cell adhesion and migration. Hsp90 binds directly to fibronectin and Hsp90 depletion regulates fibronectin matrix stability. Where inhibition of Hsp90 with a C-terminal inhibitor, novobiocin, reduced the fibronectin matrix, treatm...

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Detalles Bibliográficos
Autores principales: Dhanani, Karim Colin Hassan, Samson, William John, Edkins, Adrienne Lesley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732156/
https://www.ncbi.nlm.nih.gov/pubmed/29247221
http://dx.doi.org/10.1038/s41598-017-18061-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732156/
https://www.ncbi.nlm.nih.gov/pubmed/29247221
http://dx.doi.org/10.1038/s41598-017-18061-y

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