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Vitamin K epoxide reductase and its paralogous enzyme have different structures and functions
Vitamin K epoxide reductase (VKOR) is an essential enzyme for vitamin K-dependent carboxylation, while the physiological function of its paralogous enzyme VKOR-like (VKORL) is yet unknown. Although these two enzymes share approximately 50% protein sequence homology, the membrane topology of VKOR is...
Autores principales: | Sinhadri, Balaji Chandra Sekhar, Jin, Da-Yun, Stafford, Darrel W., Tie, Jian-Ke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732223/ https://www.ncbi.nlm.nih.gov/pubmed/29247216 http://dx.doi.org/10.1038/s41598-017-18008-3 |
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