Gp96 Peptide Antagonist gp96-II Confers Therapeutic Effects in Murine Intestinal Inflammation

BACKGROUND: The expression of heat shock protein gp96 is strongly correlated with the degree of tissue inflammation in ulcerative colitis and Crohn’s disease, thereby leading us to the hypothesis that inhibition of expression via gp96-II peptide prevents intestinal inflammation. METHODS: We employed...

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Detalles Bibliográficos
Autores principales: Nold-Petry, Claudia A., Nold, Marcel F., Levy, Ofer, Kliger, Yossef, Oren, Anat, Borukhov, Itamar, Becker, Christoph, Wirtz, Stefan, Sandhu, Manjeet K., Neurath, Markus, Dinarello, Charles A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732239/
https://www.ncbi.nlm.nih.gov/pubmed/29312281
http://dx.doi.org/10.3389/fimmu.2017.01531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732239/
https://www.ncbi.nlm.nih.gov/pubmed/29312281
http://dx.doi.org/10.3389/fimmu.2017.01531

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