Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification

Establishment of a functional vascular network is rate-limiting in embryonic development, tissue repair and engineering. During blood vessel formation, newly generated endothelial cells rapidly expand into primitive plexi that undergo vascular remodeling into circulatory networks, requiring coordina...

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Detalles Bibliográficos
Autores principales: Fang, Jennifer S., Coon, Brian G., Gillis, Noelle, Chen, Zehua, Qiu, Jingyao, Chittenden, Thomas W., Burt, Janis M., Schwartz, Martin A., Hirschi, Karen K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732288/
https://www.ncbi.nlm.nih.gov/pubmed/29247167
http://dx.doi.org/10.1038/s41467-017-01742-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732288/
https://www.ncbi.nlm.nih.gov/pubmed/29247167
http://dx.doi.org/10.1038/s41467-017-01742-7

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