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Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification
Establishment of a functional vascular network is rate-limiting in embryonic development, tissue repair and engineering. During blood vessel formation, newly generated endothelial cells rapidly expand into primitive plexi that undergo vascular remodeling into circulatory networks, requiring coordina...
Autores principales: | Fang, Jennifer S., Coon, Brian G., Gillis, Noelle, Chen, Zehua, Qiu, Jingyao, Chittenden, Thomas W., Burt, Janis M., Schwartz, Martin A., Hirschi, Karen K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732288/ https://www.ncbi.nlm.nih.gov/pubmed/29247167 http://dx.doi.org/10.1038/s41467-017-01742-7 |
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