Cargando…

Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification

Establishment of a functional vascular network is rate-limiting in embryonic development, tissue repair and engineering. During blood vessel formation, newly generated endothelial cells rapidly expand into primitive plexi that undergo vascular remodeling into circulatory networks, requiring coordina...

Descripción completa

Detalles Bibliográficos
Autores principales: Fang, Jennifer S., Coon, Brian G., Gillis, Noelle, Chen, Zehua, Qiu, Jingyao, Chittenden, Thomas W., Burt, Janis M., Schwartz, Martin A., Hirschi, Karen K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732288/
https://www.ncbi.nlm.nih.gov/pubmed/29247167
http://dx.doi.org/10.1038/s41467-017-01742-7

Ejemplares similares