Cargando…

Increasing the permeability of Escherichia coli using MAC13243

The outer membrane of gram-negative bacteria is a permeability barrier that prevents the efficient uptake of molecules with large scaffolds. As a consequence, a number of antibiotic classes are ineffective against gram-negative strains. Herein we carried out a high throughput screen for small molecu...

Descripción completa

Detalles Bibliográficos
Autores principales: Muheim, Claudio, Götzke, Hansjörg, Eriksson, Anna U., Lindberg, Stina, Lauritsen, Ida, Nørholm, Morten H. H., Daley, Daniel O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732295/
https://www.ncbi.nlm.nih.gov/pubmed/29247166
http://dx.doi.org/10.1038/s41598-017-17772-6