AICAR suppresses TNF-α-induced complement factor B in RPE cells

Age related macular degeneration is the leading cause of blindness in the developed world. Although its precise cause remains elusive, dysfunction of the retinal pigment epithelium (RPE) and dysregulation of complement have been implicated in its pathogenesis. The goal of this study was to evaluate...

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Detalles Bibliográficos
Autores principales: Chung, Eun Jee, Efstathiou, Nikolaos E., Konstantinou, Eleni K., Maidana, Daniel E., Miller, Joan W., Young, Lucy H., Vavvas, Demetrios G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732305/
https://www.ncbi.nlm.nih.gov/pubmed/29247196
http://dx.doi.org/10.1038/s41598-017-17744-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732305/
https://www.ncbi.nlm.nih.gov/pubmed/29247196
http://dx.doi.org/10.1038/s41598-017-17744-w

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