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Targeting the Conserved Fusion Loop of HAP2 Inhibits the Transmission of Plasmodium berghei and falciparum

Inhibiting transmission of Plasmodium is a central strategy in malarial eradication, and the biological process of gamete fusion during fertilization is a proven target for this approach. The lack of a structure or known molecular function of current anti-malarial vaccine targets has previously been...

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Detalles Bibliográficos
Autores principales: Angrisano, Fiona, Sala, Katarzyna A., Da, Dari F., Liu, Yanjie, Pei, Jimin, Grishin, Nick V., Snell, William J., Blagborough, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732318/
https://www.ncbi.nlm.nih.gov/pubmed/29212032
http://dx.doi.org/10.1016/j.celrep.2017.11.024