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Treatment with a New Peroxisome Proliferator-Activated Receptor Gamma Agonist, Pyridinecarboxylic Acid Derivative, Increases Angiogenesis and Reduces Inflammatory Mediators in the Heart of Trypanosoma cruzi-Infected Mice

Trypanosoma cruzi infection induces an intense inflammatory response in diverse host tissues. The immune response and the microvascular abnormalities associated with infection are crucial aspects in the generation of heart damage in Chagas disease. Upon parasite uptake, macrophages, which are involv...

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Detalles Bibliográficos
Autores principales: Penas, Federico Nicolás, Carta, Davide, Dmytrenko, Ganna, Mirkin, Gerado A., Modenutti, Carlos Pablo, Cevey, Ágata Carolina, Rada, Maria Jimena, Ferlin, Maria Grazia, Sales, María Elena, Goren, Nora Beatriz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732351/
https://www.ncbi.nlm.nih.gov/pubmed/29312293
http://dx.doi.org/10.3389/fimmu.2017.01738