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Treatment with a New Peroxisome Proliferator-Activated Receptor Gamma Agonist, Pyridinecarboxylic Acid Derivative, Increases Angiogenesis and Reduces Inflammatory Mediators in the Heart of Trypanosoma cruzi-Infected Mice
Trypanosoma cruzi infection induces an intense inflammatory response in diverse host tissues. The immune response and the microvascular abnormalities associated with infection are crucial aspects in the generation of heart damage in Chagas disease. Upon parasite uptake, macrophages, which are involv...
Autores principales: | Penas, Federico Nicolás, Carta, Davide, Dmytrenko, Ganna, Mirkin, Gerado A., Modenutti, Carlos Pablo, Cevey, Ágata Carolina, Rada, Maria Jimena, Ferlin, Maria Grazia, Sales, María Elena, Goren, Nora Beatriz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732351/ https://www.ncbi.nlm.nih.gov/pubmed/29312293 http://dx.doi.org/10.3389/fimmu.2017.01738 |
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