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Liraglutide modulates GABAergic signaling in rat hippocampal CA3 pyramidal neurons predominantly by presynaptic mechanism

BACKGROUND: γ-Aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the brain where it regulates activity of neuronal networks. The receptor for glucagon-like peptide-1 (GLP-1) is expressed in the hippocampus, which is the center for memory and learning. In this study we examined effec...

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Detalles Bibliográficos
Autores principales: Babateen, Omar, Korol, Sergiy V., Jin, Zhe, Bhandage, Amol K., Ahemaiti, Aikeremu, Birnir, Bryndis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732397/
https://www.ncbi.nlm.nih.gov/pubmed/29246184
http://dx.doi.org/10.1186/s40360-017-0191-0