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Helios + Regulatory T cell frequencies are correlated with control of viral replication and recovery of absolute CD4 T cells counts in early HIV-1 infection

BACKGROUND: The acute phase of HIV infection is characterized by massive depletion of CD4 T cells, high viral plasma levels and pronounced systemic immune activation. Regulatory T cells (Tregs) have the potential to control systemic immune activation but also to suppress antigen specific T and B cel...

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Detalles Bibliográficos
Autores principales: Matavele Chissumba, Raquel, Namalango, Eduardo, Maphossa, Vânia, Macicame, Ivalda, Bhatt, Nilesh, Polyak, Christina, Robb, Merlin, Michael, Nelson, Jani, Ilesh, Kestens, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732399/
https://www.ncbi.nlm.nih.gov/pubmed/29246111
http://dx.doi.org/10.1186/s12865-017-0235-7