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Inhibition of EGR1 inhibits glioma proliferation by targeting CCND1 promoter

BACKGROUND: Gliomas are the most common primary tumors in central nervous system. The prognosis of the patients with glioma is poor regardless of the development of therapeutic strategies. Its aggressive behavior mainly depends on the potent ability of proliferation. The transcription factor EGR1 (e...

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Detalles Bibliográficos
Autores principales: Chen, Dian-gang, Zhu, Bo, Lv, Sheng-qing, Zhu, Hongfan, Tang, Jinliang, Huang, Changlin, Li, Qingrui, Zhou, Pu, Wang, Dong-lin, Li, Guang-hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732438/
https://www.ncbi.nlm.nih.gov/pubmed/29246166
http://dx.doi.org/10.1186/s13046-017-0656-4