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Inhibition of EGR1 inhibits glioma proliferation by targeting CCND1 promoter
BACKGROUND: Gliomas are the most common primary tumors in central nervous system. The prognosis of the patients with glioma is poor regardless of the development of therapeutic strategies. Its aggressive behavior mainly depends on the potent ability of proliferation. The transcription factor EGR1 (e...
Autores principales: | Chen, Dian-gang, Zhu, Bo, Lv, Sheng-qing, Zhu, Hongfan, Tang, Jinliang, Huang, Changlin, Li, Qingrui, Zhou, Pu, Wang, Dong-lin, Li, Guang-hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732438/ https://www.ncbi.nlm.nih.gov/pubmed/29246166 http://dx.doi.org/10.1186/s13046-017-0656-4 |
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