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Identification of regulatory modules in genome scale transcription regulatory networks

BACKGROUND: In gene regulatory networks, transcription factors often function as co-regulators to synergistically induce or inhibit expression of their target genes. However, most existing module-finding algorithms can only identify densely connected genes but not co-regulators in regulatory network...

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Detalles Bibliográficos
Autores principales: Song, Qi, Grene, Ruth, Heath, Lenwood S., Li, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732458/
https://www.ncbi.nlm.nih.gov/pubmed/29246163
http://dx.doi.org/10.1186/s12918-017-0493-2