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Supersaturable solid self-microemulsifying drug delivery system: precipitation inhibition and bioavailability enhancement

Solid self-emulsifying drug delivery system (SSEDDS), which incorporates liquid SEDDS into a solid dosage form, has been recently introduced to improve the oral bioavail-ability of poorly water-soluble drugs. However, supersaturated drug generated by SSEDDS is thermodynamically unstable and tends to...

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Detalles Bibliográficos
Autores principales: Quan, Guilan, Niu, Boyi, Singh, Vikramjeet, Zhou, Yixian, Wu, Chuan-Yu, Pan, Xin, Wu, Chuanbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732552/
https://www.ncbi.nlm.nih.gov/pubmed/29263669
http://dx.doi.org/10.2147/IJN.S149717