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Supersaturable solid self-microemulsifying drug delivery system: precipitation inhibition and bioavailability enhancement
Solid self-emulsifying drug delivery system (SSEDDS), which incorporates liquid SEDDS into a solid dosage form, has been recently introduced to improve the oral bioavail-ability of poorly water-soluble drugs. However, supersaturated drug generated by SSEDDS is thermodynamically unstable and tends to...
Autores principales: | Quan, Guilan, Niu, Boyi, Singh, Vikramjeet, Zhou, Yixian, Wu, Chuan-Yu, Pan, Xin, Wu, Chuanbin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732552/ https://www.ncbi.nlm.nih.gov/pubmed/29263669 http://dx.doi.org/10.2147/IJN.S149717 |
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