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RNA polymerase III limits longevity downstream of TORC1

Three distinct RNA polymerases (Pols) transcribe different classes of genes in the eukaryotic nucleus1. Pol III is the essential, evolutionarily conserved enzyme that generates short, non-coding RNAs, including transfer RNAs (tRNAs) and 5S ribosomal RNA (rRNA)2. Historical focus on transcription of...

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Detalles Bibliográficos
Autores principales: Filer, Danny, Thompson, Maximillian A., Takhaveev, Vakil, Dobson, Adam J., Kotronaki, Ilektra, Green, James W.M., Heinemann, Matthias, Tullet, Jennifer M.A., Alic, Nazif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732570/
https://www.ncbi.nlm.nih.gov/pubmed/29186112
http://dx.doi.org/10.1038/nature25007