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Loss of p53-inducible long non-coding RNA LINC01021 increases chemosensitivity

We have previously identified the long non-coding RNA LINC01021 as a direct p53 target (Hünten et al. Mol Cell Proteomics. 2015; 14:2609-2629). Here, we show that LINC01021 is up-regulated in colorectal cancer (CRC) cell lines upon various p53-activating treatments. The LINC01021 promoter and the p5...

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Detalles Bibliográficos
Autores principales: Kaller, Markus, Götz, Ursula, Hermeking, Heiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732690/
https://www.ncbi.nlm.nih.gov/pubmed/29262524
http://dx.doi.org/10.18632/oncotarget.22245