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Prostaglandin I(2) is responsible for ameliorating prostaglandin E(2) stress in stimulating the expression of tumor necrosis factor α in a β-amyloid protein -dependent mechanism
Cyclooxygenase-2 (COX-2) has been found to be induced during the early stage of Alzheimer’s disease (AD). Using mouse-derived astrocyte and APP/PS1 transgenic (Tg) mice as model systems, we firstly elucidated the mechanisms underlying COX-2 metabolic production including prostaglandin (PG)E(2)- and...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732691/ https://www.ncbi.nlm.nih.gov/pubmed/29262525 http://dx.doi.org/10.18632/oncotarget.18462 |