APC loss in breast cancer leads to doxorubicin resistance via STAT3 activation

Resistance to chemotherapy is one of the leading causes of death from breast cancer. We recently established that loss of Adenomatous Polyposis Coli (APC) in the Mouse Mammary Tumor Virus – Polyoma middle T (MMTV-PyMT) transgenic mouse model results in resistance to cisplatin or doxorubicin-induced...

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Detalles Bibliográficos
Autores principales: VanKlompenberg, Monica K., Leyden, Emily, Arnason, Anne H., Zhang, Jian-Ting, Stefanski, Casey D., Prosperi, Jenifer R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732695/
https://www.ncbi.nlm.nih.gov/pubmed/29262529
http://dx.doi.org/10.18632/oncotarget.22263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732695/
https://www.ncbi.nlm.nih.gov/pubmed/29262529
http://dx.doi.org/10.18632/oncotarget.22263

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