Alpha-ketoglutarate suppresses the NF-κB-mediated inflammatory pathway and enhances the PXR-regulated detoxification pathway

Alpha-ketoglutarate (AKG) is a critical nutritional factor in the maintenance of intestinal homeostasis. However, the relative mechanism of AKG has not been well understood. It was recently shown that the interaction between nuclear factor kappa B (NF-κB)-mediated inflammatory pathway and pregnane X...

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Detalles Bibliográficos
Autores principales: He, Liuqin, Li, Huan, Huang, Niu, Zhou, Xihong, Tian, Junquan, Li, Tiejun, Wu, Jing, Tian, Yanan, Yin, Yulong, Yao, Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732704/
https://www.ncbi.nlm.nih.gov/pubmed/29262538
http://dx.doi.org/10.18632/oncotarget.16875

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732704/
https://www.ncbi.nlm.nih.gov/pubmed/29262538
http://dx.doi.org/10.18632/oncotarget.16875

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