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Alpha-ketoglutarate suppresses the NF-κB-mediated inflammatory pathway and enhances the PXR-regulated detoxification pathway
Alpha-ketoglutarate (AKG) is a critical nutritional factor in the maintenance of intestinal homeostasis. However, the relative mechanism of AKG has not been well understood. It was recently shown that the interaction between nuclear factor kappa B (NF-κB)-mediated inflammatory pathway and pregnane X...
Autores principales: | He, Liuqin, Li, Huan, Huang, Niu, Zhou, Xihong, Tian, Junquan, Li, Tiejun, Wu, Jing, Tian, Yanan, Yin, Yulong, Yao, Kang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732704/ https://www.ncbi.nlm.nih.gov/pubmed/29262538 http://dx.doi.org/10.18632/oncotarget.16875 |
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