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Identification of SPOP related metabolic pathways in prostate cancer

Speckle-type POZ protein (SPOP), as a cullin-based E3 ubiquitin ligase, has been identified as one of the most frequently mutated genes in prostate cancer (PCa). However, whether SPOP mutations contribute to metabolic reprogramming in PCa remains unknown. Here, integrated studies of transcriptomics...

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Detalles Bibliográficos
Autores principales: Yan, Min, Qi, Huan, Li, Jia, Ye, Guozhu, Shao, Yaping, Li, Tongming, Liu, Jing, Piao, Hai-Long, Xu, Guowang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732708/
https://www.ncbi.nlm.nih.gov/pubmed/29262542
http://dx.doi.org/10.18632/oncotarget.21460