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Crotonoside exhibits selective post-inhibition effect in AML cells via inhibition of FLT3 and HDAC3/6

Targeted therapies for the treatment of acute myeloid leukemia (AML), specifically the FLT3 inhibitors, have shown promising results. Nevertheless, it is very unlikely that inhibitors which target a single pathway will provide long-term disease control. Here, we report the characterization of croton...

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Detalles Bibliográficos
Autores principales: Li, Yu-Zhi, Yu, Si, Yan, Pei-Ao, Gong, Dao-Yin, Wu, Fang-Li, He, Zhi, Yuan, Yu-Yao, Zhao, An-Yan, Tang, Xue, Zhang, Ruo-Qi, Peng, Cheng, Cao, Zhi-Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732713/
https://www.ncbi.nlm.nih.gov/pubmed/29262547
http://dx.doi.org/10.18632/oncotarget.20710