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Inhibition of PTEN activity aggravates cisplatin-induced acute kidney injury

Cisplatin (cis-Diamminedichloroplatinum II) has been widely and effectively used in chemotherapy against tumors. Nephrotoxicity due to cisplatin is one of the most common clinical causes of acute kidney injury (AKI), which has a poor prognosis and high mortality. The signaling mechanisms underlying...

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Detalles Bibliográficos
Autores principales: Zhou, Jun, Fan, Youling, Tang, Simin, Wu, Huiping, Zhong, Jiying, Huang, Zhengxing, Yang, Chengxiang, Chen, Hongtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732719/
https://www.ncbi.nlm.nih.gov/pubmed/29262553
http://dx.doi.org/10.18632/oncotarget.20790