A niche that triggers aggressiveness within BRCA1-IRIS overexpressing triple negative tumors is supported by reciprocal interactions with the microenvironment

Production of metastasis capable precursors begins within the primary tumor. Here, we define the bidirectional interactions with stromal cells involved in promoting these precursors within BRCA1-IRIS (hereafter IRIS) overexpressing (IRISOE) TNBC tumors. We define an aggressiveness niche, functionall...

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Detalles Bibliográficos
Autores principales: Ryan, Daniel, Bogan, Danielle, Davies, Joanna, Koziol, Jim, ElShamy, Wael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732721/
https://www.ncbi.nlm.nih.gov/pubmed/29262555
http://dx.doi.org/10.18632/oncotarget.20892

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732721/
https://www.ncbi.nlm.nih.gov/pubmed/29262555
http://dx.doi.org/10.18632/oncotarget.20892

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