STAT3-mediated activation of miR-21 is involved in down-regulation of TIMP3 and neovascularization in the ischemic retina

Retinal neovascularization (RNV) is a sight threatening complication of ischemic retinopathies with limited therapeutic options. The transcription factor signal transducer and activator of transcription 3 (STAT3) has been shown to play a crucial role in promoting RNV. However, manipulating of STAT3...

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Detalles Bibliográficos
Autores principales: Gutsaeva, Diana R., Thounaojam, Menaka, Rajpurohit, Shubhra, Powell, Folami L., Martin, Pamela M., Goei, Stephanie, Duncan, Michael, Bartoli, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732751/
https://www.ncbi.nlm.nih.gov/pubmed/29262585
http://dx.doi.org/10.18632/oncotarget.21592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732751/
https://www.ncbi.nlm.nih.gov/pubmed/29262585
http://dx.doi.org/10.18632/oncotarget.21592

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